COVID19

[Sandydragon]

https://www.nytimes.com/2020/12/28/heal ... ental.html

So my brother in law had 2 psychotic incidents. Pretty much exactly as described in this article.

Pretty terrible side effect... they’ve changed medication but who knows.

His dad just died of it today, too...

This thing is seriously insidious and much worse than first thought. We need to take it seriously.

And we really don't understand the implications of 'long covid'. Describing this as a form of flu was a huge mistake, sadly too many idiots still believe that.

[Stom]

https://www.nytimes.com/2020/12/28/heal ... ental.html

So my brother in law had 2 psychotic incidents. Pretty much exactly as described in this article.

Pretty terrible side effect... they’ve changed medication but who knows.

His dad just died of it today, too...

This thing is seriously insidious and much worse than first thought. We need to take it seriously.

And we really don't understand the implications of 'long covid'. Describing this as a form of flu was a huge mistake, sadly too many idiots still believe that.

The thing is, this "post-covid psychosis" has similar examples from Spanish Flu, SARS and MERS. So this is something we could have predicted. And it's also becoming more and more obvious that the Spanish Flu pandemic was very closely related to these 3 recent epi and pandemics.

[Sandydragon]

https://www.nytimes.com/2020/12/28/heal ... ental.html

So my brother in law had 2 psychotic incidents. Pretty much exactly as described in this article.

Pretty terrible side effect... they’ve changed medication but who knows.

His dad just died of it today, too...

This thing is seriously insidious and much worse than first thought. We need to take it seriously.

And we really don't understand the implications of 'long covid'. Describing this as a form of flu was a huge mistake, sadly too many idiots still believe that.

The thing is, this "post-covid psychosis" has similar examples from Spanish Flu, SARS and MERS. So this is something we could have predicted. And it's also becoming more and more obvious that the Spanish Flu pandemic was very closely related to these 3 recent epi and pandemics.

That would have required us to have taken SARS etc seriously in the first place. Western countries either didn't take that much notice originally, assuming it to be an far eastern problem, or they did but lost interest later as money was needed for other things.

[morepork]

Each vial holds 10 doses (+ ~15% of one more). They seem fine. Needles could be interesting in a few weeks. And the gloves tear like wet shit paper when you put them on.

Not sure whether it is accumulated surplus or no-shows, but there's reports of a mix of..
- pharmacies offering unused dosage at day-end,
(presumably first-come - vaccine probs. needs using pronto), and in uk..
- peeps enquiring at close in GP's if any still going, and getting one early.
Sounds only natural and avoids wastage of the golden sauce, but the matters of prioritising vulnerables and key-workers, and contrived queue-jumping will inevitably arise.

Mixing vials for an extra dose is a big no-no. In the event of an adverse response, mixing contents from multiple vials renders it near impossible to trace the source material. Each vial is part of a specific lot, with strict QC criteria specific to each lot. If you mix lots and an adverse reaction is manifest, you will need to destroy two or more lots to try and avoid administering possible bad lots/vials. Stabbing a needle around a near empty vial in an attempt to obtain a small quantity left risks breaching the septum seal and introducing contaminants. It's a totally avoidable risk.

[Digby]

Each vial holds 10 doses (+ ~15% of one more). They seem fine. Needles could be interesting in a few weeks. And the gloves tear like wet shit paper when you put them on.

Not sure whether it is accumulated surplus or no-shows, but there's reports of a mix of..
- pharmacies offering unused dosage at day-end,
(presumably first-come - vaccine probs. needs using pronto), and in uk..
- peeps enquiring at close in GP's if any still going, and getting one early.
Sounds only natural and avoids wastage of the golden sauce, but the matters of prioritising vulnerables and key-workers, and contrived queue-jumping will inevitably arise.

Mixing vials for an extra dose is a big no-no. In the event of an adverse response, mixing contents from multiple vials renders it near impossible to trace the source material. Each vial is part of a specific lot, with strict QC criteria specific to each lot. If you mix lots and an adverse reaction is manifest, you will need to destroy two or more lots to try and avoid administering possible bad lots/vials. Stabbing a needle around a near empty vial in an attempt to obtain a small quantity left risks breaching the septum seal and introducing contaminants. It's a totally avoidable risk.

Presumably each vial holds a minimum quantity and to be sure it's a minimum some vials safely hold an additional dose? It'd make sense to utilise that and those dosages for no shows

[morepork]

Not sure whether it is accumulated surplus or no-shows, but there's reports of a mix of..
- pharmacies offering unused dosage at day-end,
(presumably first-come - vaccine probs. needs using pronto), and in uk..
- peeps enquiring at close in GP's if any still going, and getting one early.
Sounds only natural and avoids wastage of the golden sauce, but the matters of prioritising vulnerables and key-workers, and contrived queue-jumping will inevitably arise.

Mixing vials for an extra dose is a big no-no. In the event of an adverse response, mixing contents from multiple vials renders it near impossible to trace the source material. Each vial is part of a specific lot, with strict QC criteria specific to each lot. If you mix lots and an adverse reaction is manifest, you will need to destroy two or more lots to try and avoid administering possible bad lots/vials. Stabbing a needle around a near empty vial in an attempt to obtain a small quantity left risks breaching the septum seal and introducing contaminants. It's a totally avoidable risk.

Presumably each vial holds a minimum quantity and to be sure it's a minimum some vials safely hold an additional dose? It'd make sense to utilise that and those dosages for no shows

each vial holds a guaranteed number of doses plus some extra for loss incurred by repeated withdrawal. That extra is not equivalent to another dose, it is a margin of safety. you have to combine extra from multiple vials to make up an additional dose. You don' thaw vials on the strength of an informal agreement to show up, you thaw them in proportion to people that have shown up. Bear in mind that thawing starts a clock ticking for shelf life, which is about 5 hours for the Moderna and Pfizer products. Clinical trial efficacy metrics are based on use within this time frame so if at the end of a 10 hour day you have <0.5ml in used vials, those metrics do not apply. What you are suggesting would introduce variability that cannot be controlled for by clinical trial data, with safety a potential variable. An uncontrolled variable will torpedo the whole effort. Data, not speculation after the fact drives this.

[Galfon]

The traceability & contamination points make sense.
Not sure where the report on radio 2 this morning about these ad hoc quickies came from, but some interesting brucie-bonus observations here..
https://www.nytimes.com/2020/12/16/heal ... doses.html

[morepork]

The traceability & contamination points make sense.
Not sure where the report on radio 2 this morning about these ad hoc quickies came from, but some interesting brucie-bonus observations here..
https://www.nytimes.com/2020/12/16/heal ... doses.html

That's optimistic. Some vials have more than others, but its a bubbly mess in the syringe that draws it.

[Galfon]

The attitude towards vaccines internationally is inconsistent to say the least..Fra: over 50% 'not keen', Some in UK declining Pfizer until Eng one available, Iran banning US/UK vaccines..
Meanwhile lockdown enthusiasm appears to have waned through covid-weariness : TfL report over 70% normal traffic levels (30% in l/down 1) and some schools are getting 50%+ attendance, partly due to digital divide.
I don't think peeps are terrified any more, and find isolation in a cold january not so easy.Frustrating for those in charge trying to keep the lid on.

[morepork]

The attitude towards vaccines internationally is inconsistent to say the least..Fra: over 50% 'not keen', Some in UK declining Pfizer until Eng one available, Iran banning US/UK vaccines..
Meanwhile lockdown enthusiasm appears to have waned through covid-weariness : TfL report over 70% normal traffic levels (30% in l/down 1) and some schools are getting 50%+ attendance, partly due to digital divide.
I don't think peeps are terrified any more, and find isolation in a cold january not so easy.Frustrating for those in charge trying to keep the lid on.

There is no cure for stupid. Political ideology hampering medicine. Again.

[Galfon]

'The northern Chinese province of Hebei reported 40 new locally transmitted coronavirus cases, with all of them in the capital city of Shijiazhuang, about 186 miles sth. of Beijing..' (bloombrg.)
Could be a test of the iron resolve and of course transparency, if it reaches Beijing. The New Year is late this year (next month) and that usually sees alot of travelling.
[Not sure if this is the go-faster variant identified in Kent, that has already been seen and thus far contained, in Shanghai.]

[Eugene Wrayburn]

The traceability & contamination points make sense.
Not sure where the report on radio 2 this morning about these ad hoc quickies came from, but some interesting brucie-bonus observations here..
https://www.nytimes.com/2020/12/16/heal ... doses.html

Britain had that 6th dose issue. Advice is now to use it.

The other bonuses weren't mixing of vials but just the fact that doses not used at the end of the day are being chucked out. Thus if there's a no show or there are others left over - I'm presuming they crack open some extra in case of breakages rather than risking sending people home disappointed - doctors were vaccinating anyone around. I definitely don't care about that. The NY position of fining doctors and hospitals if they give it out of priority order is fucking insane. Every person vaccinated is a bonus for everyone regardless of where they were in the queue.

[morepork]

The traceability & contamination points make sense.
Not sure where the report on radio 2 this morning about these ad hoc quickies came from, but some interesting brucie-bonus observations here..
https://www.nytimes.com/2020/12/16/heal ... doses.html

Britain had that 6th dose issue. Advice is now to use it.

The other bonuses weren't mixing of vials but just the fact that doses not used at the end of the day are being chucked out. Thus if there's a no show or there are others left over - I'm presuming they crack open some extra in case of breakages rather than risking sending people home disappointed - doctors were vaccinating anyone around. I definitely don't care about that. The NY position of fining doctors and hospitals if they give it out of priority order is fucking insane. Every person vaccinated is a bonus for everyone regardless of where they were in the queue.

As long as the dose given is within the time frame accommodated by clinical trial parameters, yes, but outside of that window is experiment, not treatment.

[Galfon]

Countries like UK, It & Spa have taken a big hit so the Vacc response is understandable - but Fra & Bel current position looks poor thus far:

Eur, doses/100  (11/1, ourworldindata/dm.)

1. Uk 4.19
2. Den 2.02
3. Ice1.43
4. Ita 1.20
5. Slo 1.08
6.Spa 0.87
7.Est 0.83...

..18.Fra 0.21
19. Net 0.21
20. Bul 0.20
21. Cze 0.19
22. Lux 0.19
23. Ser 0.14
24. Bel 0.07

Ireland appears to be now under the cosh -
New cases/100k:
Ire 5.6 ( dec 13 ).. 132.2 ( jan 10 )
uk 89.3 (jan 10).
Not sure if it was Xmas festivities or new variant travelling over from uk (certainly can't blame Brexit..), this could pose real problems in a week or 2.

[paddy no 11]

Combination of Christmas and new variant which now accounts for 50% of all cases

Hospitals are not quite fucked but we'll be like bergamot in days

Cases will fall quickly but damage is done

[Galfon]

Sometimes it appears earthlings strings are being pulled/the fickle finger of fate..
WHO arrive, first death in 9m. reported. (consistent with recent case numbers tbf).
https://www.theguardian.com/world/2021/ ... s-in-wuhan

[Galfon]

More positively, MumG (late 80's, lives alone in midlands) had her first shot today at a med. centre in a nearby town - quickly done, no waiting, hour round trip from home - bigUp to the WussPCT.

[Which Tyler]

[Which Tyler]

I really, really hate the "if you're not dead, you're fine" false-narrative around this virus

https://metro.co.uk/2021/01/18/one-in-e ... -13920415/

A third of people who recovered after suffering from severe Covid were readmitted to hospital within five months with complications including heart problems, diabetes and chronic liver and kidney conditions.

New research has shown the devastating long term impact of the virus with one in eight people dying within five months of diagnosis.

The University of Leicester and the Office for National Statistics found that out of 47,780 people discharged from hospital in the first wave, 29.4% were back in hospital within 140 days and 12.3% died.

Covid survivors were three and half times more likely to be readmitted to hospital and die compared to other conditions.


Read more: https://metro.co.uk/2021/01/18/one-in-e ... to=cbshare

Twitter: https://twitter.com/MetroUK | Facebook: https://www.facebook.com/MetroUK/

[Sandydragon]

I really, really hate the "if you're not dead, you're fine" false-narrative around this virus

https://metro.co.uk/2021/01/18/one-in-e ... -13920415/

A third of people who recovered after suffering from severe Covid were readmitted to hospital within five months with complications including heart problems, diabetes and chronic liver and kidney conditions.

New research has shown the devastating long term impact of the virus with one in eight people dying within five months of diagnosis.

The University of Leicester and the Office for National Statistics found that out of 47,780 people discharged from hospital in the first wave, 29.4% were back in hospital within 140 days and 12.3% died.

Covid survivors were three and half times more likely to be readmitted to hospital and die compared to other conditions.


Read more: https://metro.co.uk/2021/01/18/one-in-e ... to=cbshare

Twitter: https://twitter.com/MetroUK | Facebook: https://www.facebook.com/MetroUK/

But it only kills those who are already sick!! FFS.

[Stom]

I really, really hate the "if you're not dead, you're fine" false-narrative around this virus

https://metro.co.uk/2021/01/18/one-in-e ... -13920415/

A third of people who recovered after suffering from severe Covid were readmitted to hospital within five months with complications including heart problems, diabetes and chronic liver and kidney conditions.

New research has shown the devastating long term impact of the virus with one in eight people dying within five months of diagnosis.

The University of Leicester and the Office for National Statistics found that out of 47,780 people discharged from hospital in the first wave, 29.4% were back in hospital within 140 days and 12.3% died.

Covid survivors were three and half times more likely to be readmitted to hospital and die compared to other conditions.


Read more: https://metro.co.uk/2021/01/18/one-in-e ... to=cbshare

Twitter: https://twitter.com/MetroUK | Facebook: https://www.facebook.com/MetroUK/

But it only kills those who are already sick!! FFS.

Killed one of my relatives who had no major underlying illness. And hospitalized another with psychosis who was as fit as a butchers dog and 40.

So, no, it can kill anyone. Just much less likely if you’re fit and healthy.

[Puja]

I really, really hate the "if you're not dead, you're fine" false-narrative around this virus

https://metro.co.uk/2021/01/18/one-in-e ... -13920415/

But it only kills those who are already sick!! FFS.

Killed one of my relatives who had no major underlying illness. And hospitalized another with psychosis who was as fit as a butchers dog and 40.

So, no, it can kill anyone. Just much less likely if you’re fit and healthy.

I believe Sandy's being sarky.

Puja

[Sandydragon]

But it only kills those who are already sick!! FFS.

Killed one of my relatives who had no major underlying illness. And hospitalized another with psychosis who was as fit as a butchers dog and 40.

So, no, it can kill anyone. Just much less likely if you’re fit and healthy.

I believe Sandy's being sarky.

Puja

I am absolutely being sarcastic Stom. That comment is repeated too often in social media and its clear that too many people hold that opinion.

[Puja]

I really, really hate the "if you're not dead, you're fine" false-narrative around this virus

https://metro.co.uk/2021/01/18/one-in-e ... -13920415/

A third of people who recovered after suffering from severe Covid were readmitted to hospital within five months with complications including heart problems, diabetes and chronic liver and kidney conditions.

New research has shown the devastating long term impact of the virus with one in eight people dying within five months of diagnosis.

The University of Leicester and the Office for National Statistics found that out of 47,780 people discharged from hospital in the first wave, 29.4% were back in hospital within 140 days and 12.3% died.

Covid survivors were three and half times more likely to be readmitted to hospital and die compared to other conditions.


Read more: https://metro.co.uk/2021/01/18/one-in-e ... to=cbshare

Twitter: https://twitter.com/MetroUK | Facebook: https://www.facebook.com/MetroUK/

I have a question about those statistics on re-reading. Is that 12.3% of the 47,780, or 12.3% of the 29.4%? Cause one of those is 5,877 deaths and one is 1,728 deaths.

I mean, it's still incredibly worrying either way, but one of those is far worse than the other.

Puja

[Stom]

Killed one of my relatives who had no major underlying illness. And hospitalized another with psychosis who was as fit as a butchers dog and 40.

So, no, it can kill anyone. Just much less likely if you’re fit and healthy.

I believe Sandy's being sarky.

Puja

I am absolutely being sarcastic Stom. That comment is repeated too often in social media and its clear that too many people hold that opinion.

Yeah, sorry. I've kinda had enough of them...

I need to get back to my news blackout...